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Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones
Splicing is catalyzed by the spliceosome, a complex of five major small nuclear ribonucleoprotein particles (snRNPs). The pre-mRNA splicing factor PRPF8 is a crucial component of the U5 snRNP, and together with EFTUD2 and SNRNP200, it forms a central module of the spliceosome. Using quantitative pro...
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| Veröffentlicht in: | J Cell Biol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5461031/ https://ncbi.nlm.nih.gov/pubmed/28515276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201701165 |
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