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TSSC4 is a component of U5 snRNP that promotes tri-snRNP formation

U5 snRNP is a complex particle essential for RNA splicing. U5 snRNPs undergo intricate biogenesis that ensures that only a fully mature particle assembles into a splicing competent U4/U6•U5 tri-snRNP and enters the splicing reaction. During splicing, U5 snRNP is substantially rearranged and leaves a...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Klimešová, Klára, Vojáčková, Jitka, Radivojević, Nenad, Vandermoere, Franck, Bertrand, Edouard, Verheggen, Celine, Staněk, David
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206348/
https://ncbi.nlm.nih.gov/pubmed/34131137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23934-y
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