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The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation

The U5 snRNP plays an essential role in both U2- and U12-dependent splicing. Here, we have characterized a 52-kDa protein associated with the human U5 snRNP, designated U5-52K. Protein sequencing revealed that U5-52K is identical to the CD2BP2, which interacts with the cytoplasmic portion of the hum...

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Detalhes bibliográficos
Main Authors: LAGGERBAUER, BERNHARD, LIU, SUNBIN, MAKAROV, EVGENY, VORNLOCHER, HANS-PETER, MAKAROVA, OLGA, INGELFINGER, DIERK, ACHSEL, TILMANN, LÜHRMANN, REINHARD
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370748/
https://ncbi.nlm.nih.gov/pubmed/15840814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2300805
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