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Tyrosine Kinase Inhibitors Are Potent Acute Pulmonary Vasodilators in Rats

Tyrosine kinase inhibitors are promising for the treatment of severe pulmonary hypertension. Their therapeutic effects are postulated to be due to inhibition of cell growth–related kinases and attenuation of vascular remodeling. Their potential vasodilatory activities have not been explored. Vasorel...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Respir Cell Mol Biol
Hauptverfasser: Abe, Kohtaro, Toba, Michie, Alzoubi, Abdallah, Koubsky, Karel, Ito, Masako, Ota, Hiroki, Gairhe, Salina, Gerthoffer, William T., Fagan, Karen A., McMurtry, Ivan F., Oka, Masahiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460892/
https://ncbi.nlm.nih.gov/pubmed/21378262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0371OC
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