Conjugation of squalene to gemcitabine as unique approach exploiting endogenous lipoproteins for drug delivery

Once introduced in the organism, the interaction of nanoparticles with various biomolecules strongly impacts their fate. Here we show that nanoparticles made of the squalene derivative of gemcitabine (SQGem) interact with lipoproteins (LPs), indirectly enabling the targeting of cancer cells with hig...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nat Commun
Main Authors: Sobot, Dunja, Mura, Simona, Yesylevskyy, Semen O., Dalbin, Laura, Cayre, Fanny, Bort, Guillaume, Mougin, Julie, Desmaële, Didier, Lepetre-Mouelhi, Sinda, Pieters, Grégory, Andreiuk, Bohdan, Klymchenko, Andrey S., Paul, Jean-Louis, Ramseyer, Christophe, Couvreur, Patrick
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459998/
https://ncbi.nlm.nih.gov/pubmed/28555624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15678
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍