Caricamento...

A new painkiller nanomedicine to bypass the blood-brain barrier and the use of morphine

The clinical use of endogenous neuropeptides has historically been limited due to pharmacokinetic issues, including plasma stability and blood-brain barrier permeability. In this study, we show that the rapidly metabolized Leu-enkephalin (LENK) neuropeptide may become pharmacologically efficient owi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Adv
Autori principali: Feng, Jiao, Lepetre-Mouelhi, Sinda, Gautier, Anne, Mura, Simona, Cailleau, Catherine, Coudore, François, Hamon, Michel, Couvreur, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374102/
https://ncbi.nlm.nih.gov/pubmed/30788432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau5148
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !