Circulating Lipoproteins: A Trojan Horse Guiding Squalenoylated Drugs to LDL-Accumulating Cancer Cells

Selective delivery of anticancer drugs to rapidly growing cancer cells can be achieved by taking advantage of their high receptor-mediated uptake of low-density lipoproteins (LDLs). Indeed, we have recently discovered that nanoparticles made of the squalene derivative of the anticancer agent gemcita...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Sobot, Dunja, Mura, Simona, Rouquette, Marie, Vukosavljevic, Branko, Cayre, Fanny, Buchy, Eric, Pieters, Grégory, Garcia-Argote, Sébastien, Windbergs, Maike, Desmaële, Didier, Couvreur, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498828/
https://ncbi.nlm.nih.gov/pubmed/28606375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.05.016
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