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The p400 E1A-associated protein is a novel component of the p53 → p21 senescence pathway

Adenovirus E1A-associated p400 belongs to the SWI2/SNF2 family of chromatin remodeling proteins. Here, we report that p400 is a component of the p53–p21(WAF1/CIP1/sid1) pathway, regulating the p21 transcription and senescence induction program. Acute depletion of p400 expression by shRNA (short hair...

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Détails bibliographiques
Auteurs principaux: Chan, Ho Man, Narita, Masako, Lowe, Scott W., Livingston, David M.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC545875/
https://ncbi.nlm.nih.gov/pubmed/15655109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1280205
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