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The p400 E1A-associated protein is a novel component of the p53 → p21 senescence pathway
Adenovirus E1A-associated p400 belongs to the SWI2/SNF2 family of chromatin remodeling proteins. Here, we report that p400 is a component of the p53–p21(WAF1/CIP1/sid1) pathway, regulating the p21 transcription and senescence induction program. Acute depletion of p400 expression by shRNA (short hair...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545875/ https://ncbi.nlm.nih.gov/pubmed/15655109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1280205 |
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