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BS69 is involved in cellular senescence through the p53–p21Cip1 pathway

The multidomain-containing cellular protein BS69 interacts with adenovirus E1A and several other viral and cellular factors, and acts as a transcription repressor. Here, we show that BS69 is involved in the p53–p21Cip1-mediated senescence pathway. Knockdown of BS69 by RNA interference in human prima...

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Detalhes bibliográficos
Main Authors: Zhang, Wei, Chan, Ho Man, Gao, Yan, Poon, Randy, Wu, Zhenguo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2002549/
https://ncbi.nlm.nih.gov/pubmed/17721438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401049
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