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Cooperation between p21 and Akt is required for p53‐dependent cellular senescence

Cellular senescence has been implicated in normal aging, tissue homeostasis, and tumor suppression. Although p53 has been shown to be a central mediator of cellular senescence, the signaling pathway by which it induces senescence remains incompletely understood. In this study, we have shown that bot...

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Enregistré dans:
Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Kim, Young Yeon, Jee, Hye Jin, Um, Jee‐Hyun, Kim, Young Mi, Bae, Sun Sik, Yun, Jeanho
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595696/
https://ncbi.nlm.nih.gov/pubmed/28691365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12639
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