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Cooperation between p21 and Akt is required for p53‐dependent cellular senescence

Cellular senescence has been implicated in normal aging, tissue homeostasis, and tumor suppression. Although p53 has been shown to be a central mediator of cellular senescence, the signaling pathway by which it induces senescence remains incompletely understood. In this study, we have shown that bot...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Kim, Young Yeon, Jee, Hye Jin, Um, Jee‐Hyun, Kim, Young Mi, Bae, Sun Sik, Yun, Jeanho
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595696/
https://ncbi.nlm.nih.gov/pubmed/28691365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12639
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