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Akt3 knockdown induces mitochondrial dysfunction in human cancer cells

Akt/PKB plays a pivotal role in cell proliferation and survival. However, the isotype-specific roles of Akt in mitochondrial function have not been fully addressed. In this study, we explored the role of Akt in mitochondrial function after stable knockdown of the Akt isoforms in EJ human bladder can...

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Detalhes bibliográficos
Publicado no:Acta Biochim Biophys Sin (Shanghai)
Main Authors: Kim, Minjee, Kim, Young Yeon, Jee, Hye Jin, Bae, Sun Sik, Jeong, Na Young, Um, Jee-Hyun, Yun, Jeanho
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888356/
https://ncbi.nlm.nih.gov/pubmed/26972278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gmw014
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