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BS69 is involved in cellular senescence through the p53–p21Cip1 pathway
The multidomain-containing cellular protein BS69 interacts with adenovirus E1A and several other viral and cellular factors, and acts as a transcription repressor. Here, we show that BS69 is involved in the p53–p21Cip1-mediated senescence pathway. Knockdown of BS69 by RNA interference in human prima...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2002549/ https://ncbi.nlm.nih.gov/pubmed/17721438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401049 |
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