Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells

Post-translational mechanisms regulating cell-matrix adhesion turnover during cell locomotion are not fully elucidated. In this study, we uncovered an essential role of Y118 site-specific tyrosine phosphorylation of paxillin, an adapter protein of focal adhesion complexes, in paxillin recruitment to...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chang, Chia-Hao, Bijian, Krikor, Qiu, Dinghong, Su, Jie, Saad, Amine, Dahabieh, Michael S, Miller, Wilson H, Alaoui-Jamali, Moulay A
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458201/
https://ncbi.nlm.nih.gov/pubmed/28415719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16105
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