Focal Adhesion Kinase-Related Proline-Rich Tyrosine Kinase 2 and Focal Adhesion Kinase Are Co-Overexpressed in Early-Stage and Invasive ErbB-2-Positive Breast Cancer and Cooperate for Breast Cancer Cell Tumorigenesis and Invasiveness

Early cancer cell migration and invasion of neighboring tissues are mediated by multiple events, including activation of focal adhesion signaling. Key regulators include the focal adhesion kinase (FAK) and FAK-related proline-rich tyrosine kinase 2 (Pyk2), whose distinct functions in cancer progress...

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Autores principales: Behmoaram, Emy, Bijian, Krikor, Jie, Su, Xu, Yingjie, Darnel, Andrew, Bismar, Tarek A., Alaoui-Jamali, Moulay A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2008
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570143/
https://ncbi.nlm.nih.gov/pubmed/18832579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080292
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