FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion

The overexpression of members of the ErbB tyrosine kinase receptor family has been associated with cancer progression. We demonstrate that focal adhesion kinase (FAK) is essential for oncogenic transformation and cell invasion that is induced by ErbB-2 and -3 receptor signaling. ErbB-2/3 overexpress...

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Detalhes bibliográficos
Main Authors: Benlimame, Naciba, He, Qiang, Jie, Su, Xiao, Dingzhang, Xu, Ying Jie, Loignon, Martin, Schlaepfer, David D., Alaoui-Jamali, Moulay A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171271/
https://ncbi.nlm.nih.gov/pubmed/16275754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200504124
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