FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion

The overexpression of members of the ErbB tyrosine kinase receptor family has been associated with cancer progression. We demonstrate that focal adhesion kinase (FAK) is essential for oncogenic transformation and cell invasion that is induced by ErbB-2 and -3 receptor signaling. ErbB-2/3 overexpress...

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Autori principali: Benlimame, Naciba, He, Qiang, Jie, Su, Xiao, Dingzhang, Xu, Ying Jie, Loignon, Martin, Schlaepfer, David D., Alaoui-Jamali, Moulay A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2005
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171271/
https://ncbi.nlm.nih.gov/pubmed/16275754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200504124
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