FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion

The overexpression of members of the ErbB tyrosine kinase receptor family has been associated with cancer progression. We demonstrate that focal adhesion kinase (FAK) is essential for oncogenic transformation and cell invasion that is induced by ErbB-2 and -3 receptor signaling. ErbB-2/3 overexpress...

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Bibliografiska uppgifter
Huvudupphovsmän: Benlimame, Naciba, He, Qiang, Jie, Su, Xiao, Dingzhang, Xu, Ying Jie, Loignon, Martin, Schlaepfer, David D., Alaoui-Jamali, Moulay A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2005
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171271/
https://ncbi.nlm.nih.gov/pubmed/16275754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200504124
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