Targeting focal adhesion turnover in invasive breast cancer cells by the purine derivative reversine

BACKGROUND: The dynamics of focal adhesion (FA) turnover is a key determinant for the regulation of cancer cell migration. Here we investigated FA turnover in a panel of breast cancer models with distinct invasive properties and evaluated the impact of reversine on this turnover in relation to cance...

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Detalhes bibliográficos
Main Authors: Bijian, K, Lougheed, C, Su, J, Xu, B, Yu, H, Wu, J H, Riccio, K, Alaoui-Jamali, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844920/
https://ncbi.nlm.nih.gov/pubmed/24169345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.675
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