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Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2

Fascin 1 (FSCN1) is a cytoskeleton-associated protein recognized to function primarily in the regulation of cytoskeleton structure and formation of plasma membrane protrusions. Here we report a novel nuclear function for Fascin 1. Biochemical studies and genome wide localization using ChIP-seq ident...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Saad, Amine, Bijian, Krikor, Qiu, Dinghong, da Silva, Sabrina Daniela, Marques, Maud, Chang, Chia-Hao, Nassour, Hassan, Ramotar, Dindial, Damaraju, Sambasivarao, Mackey, John, Bismar, Tarek, Witcher, Michael, Alaoui-Jamali, Moulay A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098188/
https://ncbi.nlm.nih.gov/pubmed/27819326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36699
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