Peroxiredoxin 1 interacts with and blocks the redox factor APE1 from activating interleukin-8 expression

APE1 is an essential DNA repair protein that also possesses the ability to regulate transcription. It has a unique cysteine residue C65, which maintains the reduce state of several transcriptional activators such as NF-κB. How APE1 is being recruited to execute the various biological functions remai...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Nassour, Hassan, Wang, Zhiqiang, Saad, Amine, Papaluca, Arturo, Brosseau, Nicolas, Affar, El Bachir, Alaoui-Jamali, Moulay A., Ramotar, Dindial
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937415/
https://ncbi.nlm.nih.gov/pubmed/27388124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29389
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