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Silencing of the Ca(v)3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception

Analgesic therapies are still limited and sometimes poorly effective, therefore finding new targets for the development of innovative drugs is urgently needed. In order to validate the potential utility of blocking T-type calcium channels to reduce nociception, we explored the effects of intrathecal...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Bourinet, Emmanuel, Alloui, Abdelkrim, Monteil, Arnaud, Barrère, Christian, Couette, Brigitte, Poirot, Olivier, Pages, Anne, McRory, John, Snutch, Terrance P, Eschalier, Alain, Nargeot, Joël
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2004
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545807/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616581/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600515
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