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Functional role of L-type Ca(v)1.3 Ca(2+) channels in cardiac pacemaker activity

The spontaneous activity of pacemaker cells in the sino-atrial node (SAN) controls the heart rhythm and rate under physiological conditions. Pacemaker activity in SAN cells is due to the presence of the diastolic depolarization, a slow depolarization phase that drives the membrane voltage from the e...

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Detalles Bibliográficos
Main Authors: Mangoni, Matteo E., Couette, Brigitte, Bourinet, Emmanuel, Platzer, Josef, Reimer, Daniel, Striessnig, Jörg, Nargeot, Joël
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC154381/
https://ncbi.nlm.nih.gov/pubmed/12700358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0935295100
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