T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome

The symptoms of irritable bowel syndrome (IBS) include significant abdominal pain and bloating. Current treatments are empirical and often poorly efficacious, and there is a need for the development of new and efficient analgesics aimed at IBS patients. T-type calcium channels have previously been v...

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Autors principals: Marger, Fabrice, Gelot, Agathe, Alloui, Abdelkrim, Matricon, Julien, Ferrer, Juan F. Sanguesa, Barrère, Christian, Pizzoccaro, Anne, Muller, Emilie, Nargeot, Joël, Snutch, Terrance P., Eschalier, Alain, Bourinet, Emmanuel, Ardid, Denis
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131334/
https://ncbi.nlm.nih.gov/pubmed/21690417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100869108
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