Silencing of the Ca(v)3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception

Analgesic therapies are still limited and sometimes poorly effective, therefore finding new targets for the development of innovative drugs is urgently needed. In order to validate the potential utility of blocking T-type calcium channels to reduce nociception, we explored the effects of intrathecal...

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Detalhes bibliográficos
Main Authors: Bourinet, Emmanuel, Alloui, Abdelkrim, Monteil, Arnaud, Barrère, Christian, Couette, Brigitte, Poirot, Olivier, Pages, Anne, McRory, John, Snutch, Terrance P, Eschalier, Alain, Nargeot, Joël
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545807/
https://ncbi.nlm.nih.gov/pubmed/15616581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600515
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