Focal Adhesion Kinase as a Potential Target in AML and MDS

Although overexpression/activation of focal adhesion kinase (FAK) is widely known in solid tumors to control cell growth, survival, invasion, metastasis, gene expression, and stem cell self-renewal, its expression and function in myeloid leukemia are not well investigated. Using reverse-phase protei...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Carter, Bing Z, Mak, Po Yee, Wang, Xiangmeng, Yang, Hui, Garcia-Manero, Guillermo, Mak, Duncan, Mu, Hong, Ruvolo, Vivian, Qiu, Yihua, Coombes, Kevin, Zhang, Nianxiang, Ragon, Brittany, Weaver, David T., Pachter, Jonathan A., Kornblau, Steven, Andreeff, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457713/
https://ncbi.nlm.nih.gov/pubmed/28270436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0719
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