Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels

PURPOSE: T cells genetically modified to express chimeric antigen receptors (CARs) targeting CD19 (CAR-19) have potent activity against acute lymphoblastic leukemia, but fewer results supporting treatment of lymphoma with CAR-19 T cells have been published. Patients with lymphoma that is chemotherap...

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Bibliografiske detaljer
Udgivet i:J Clin Oncol
Main Authors: Kochenderfer, James N., Somerville, Robert P.T., Lu, Tangying, Shi, Victoria, Bot, Adrian, Rossi, John, Xue, Allen, Goff, Stephanie L., Yang, James C., Sherry, Richard M., Klebanoff, Christopher A., Kammula, Udai S., Sherman, Marika, Perez, Arianne, Yuan, Constance M., Feldman, Tatyana, Friedberg, Jonathan W., Roschewski, Mark J., Feldman, Steven A., McIntyre, Lori, Toomey, Mary Ann, Rosenberg, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2017
Fag:
Original Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455597/
https://ncbi.nlm.nih.gov/pubmed/28291388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.71.3024
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