Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels

PURPOSE: T cells genetically modified to express chimeric antigen receptors (CARs) targeting CD19 (CAR-19) have potent activity against acute lymphoblastic leukemia, but fewer results supporting treatment of lymphoma with CAR-19 T cells have been published. Patients with lymphoma that is chemotherap...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Kochenderfer, James N., Somerville, Robert P.T., Lu, Tangying, Shi, Victoria, Bot, Adrian, Rossi, John, Xue, Allen, Goff, Stephanie L., Yang, James C., Sherry, Richard M., Klebanoff, Christopher A., Kammula, Udai S., Sherman, Marika, Perez, Arianne, Yuan, Constance M., Feldman, Tatyana, Friedberg, Jonathan W., Roschewski, Mark J., Feldman, Steven A., McIntyre, Lori, Toomey, Mary Ann, Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2017
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455597/
https://ncbi.nlm.nih.gov/pubmed/28291388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.71.3024
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