Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory elementbinding protein-1c

Sterol regulatory element-binding proteins (SREBPs) are transcription factors central to the regulation of lipid metabolism. The SREBPs are synthesized as precursor proteins that require proteolytic processing to become transcriptionally active. Whereas the regulation of SREBP-1a and -2 cleavage by...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Hegarty, Bronwyn D., Bobard, Alexandre, Hainault, Isabelle, Ferré, Pascal, Bossard, Pascale, Foufelle, Fabienne
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15637161/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0405067102
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