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Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.

The transcription factor sterol regulatory-element-binding protein-1c (SREBP-1c) plays a major role in the effect of insulin on the transcription of hepatic genes such as glucokinase and fatty acid synthase. We show here in cultured rat hepatocytes that insulin, through activation of the phosphatidy...

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Bibliografiske detaljer
Main Authors: Azzout-Marniche, D, Bécard, D, Guichard, C, Foretz, M, Ferré, P, Foufelle, F
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221265/
https://ncbi.nlm.nih.gov/pubmed/10947952
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