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Insulin activates human sterol-regulatory-element-binding protein-1c (SREBP-1c) promoter through SRE motifs

In the present study, we aimed to decipher the mechanisms involved in the transcriptional effect of insulin on the SREBP-1c specific promoter of the human srebf-1 gene. Using luciferase reporter gene constructs in HEK-293 cells (human embryonic kidney cells), we demonstrated that the full effect of...

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Detalhes bibliográficos
Main Authors: Dif, Nicolas, Euthine, Vanessa, Gonnet, Estelle, Laville, Martine, Vidal, Hubert, Lefai, Etienne
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635455/
https://ncbi.nlm.nih.gov/pubmed/16831124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060499
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