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Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
Hepatic glucokinase plays a key role in glucose metabolism as underlined by the anomalies associated with glucokinase mutations and the consequences of tissue-specific knock-out. In the liver, glucokinase transcription is absolutely dependent on the presence of insulin. The cis-elements and trans-ac...
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Autores principales: | , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
The National Academy of Sciences
1999
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23076/ https://ncbi.nlm.nih.gov/pubmed/10535992 |
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