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Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

Hepatic glucokinase plays a key role in glucose metabolism as underlined by the anomalies associated with glucokinase mutations and the consequences of tissue-specific knock-out. In the liver, glucokinase transcription is absolutely dependent on the presence of insulin. The cis-elements and trans-ac...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Foretz, Marc, Guichard, Colette, Ferré, Pascal, Foufelle, Fabienne
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1999
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23076/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535992/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12737
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