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Human Sterol Regulatory Element-Binding Protein 1a Contributes Significantly to Hepatic Lipogenic Gene Expression

Background/Aims: Sterol regulatory element-binding protein (SREBP) 1, the master regulator of lipogenesis, was shown to be associated with non-alcoholic fatty liver disease, which is attributed to its major isoform SREBP1c. Based on studies in mice, the minor isoform SREBP1a is regarded as negligibl...

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Autors principals: Andreas Bitter, Andreas K. Nüssler, Wolfgang E. Thasler, Kathrin Klein, Ulrich M. Zanger, Matthias Schwab, Oliver Burk
Format: Artigo
Idioma:Inglês
Publicat: Cell Physiol Biochem Press GmbH & Co KG 2015-01-01
Col·lecció:Cellular Physiology and Biochemistry
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Accés en línia:http://www.karger.com/Article/FullText/369739
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