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Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory elementbinding protein-1c

Sterol regulatory element-binding proteins (SREBPs) are transcription factors central to the regulation of lipid metabolism. The SREBPs are synthesized as precursor proteins that require proteolytic processing to become transcriptionally active. Whereas the regulation of SREBP-1a and -2 cleavage by...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hegarty, Bronwyn D., Bobard, Alexandre, Hainault, Isabelle, Ferré, Pascal, Bossard, Pascale, Foufelle, Fabienne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15637161/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0405067102
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