Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP

YAP is a transcriptional coactivator that controls organ expansion and differentiation and is inhibited by the Hippo pathway in cells in interphase. Here, we demonstrated that, during mitosis, YAP localized to the midbody and spindle, subcellular structures that are involved in cytokinesis, the proc...

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Udgivet i:Sci Signal
Main Authors: Bui, Duyen Amy, Lee, Wendy, White, Anne E., Harper, J. Wade, Schackmann, Ron C. J., Overholtzer, Michael, Selfors, Laura M., Brugge, Joan S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455055/
https://ncbi.nlm.nih.gov/pubmed/26933062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa9227
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