Hippo Pathway Effector Yap is an Ovarian Cancer Oncogene

The Hippo Pathway regulates organ size and tumorigenesis in Drosophila and mammals and is altered in a variety of human cancers, yet it remains unclear if the Hippo Pathway is of prognostic significance to cancer patients. Here we show that Yap, the human homolog of the key transcriptional target of...

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Bibliografiske detaljer
Main Authors: Hall, Chad A., Wang, Runsheng, Miao, Jiangyong, Oliva, Esther, Shen, Xiaoyun, Wheeler, Thomas, Hilsenbeck, Susan G., Orsulic, Sandra, Goode, Scott
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970655/
https://ncbi.nlm.nih.gov/pubmed/20947521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1242
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