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Hippo Pathway Effector Yap is an Ovarian Cancer Oncogene

The Hippo Pathway regulates organ size and tumorigenesis in Drosophila and mammals and is altered in a variety of human cancers, yet it remains unclear if the Hippo Pathway is of prognostic significance to cancer patients. Here we show that Yap, the human homolog of the key transcriptional target of...

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Autors principals: Hall, Chad A., Wang, Runsheng, Miao, Jiangyong, Oliva, Esther, Shen, Xiaoyun, Wheeler, Thomas, Hilsenbeck, Susan G., Orsulic, Sandra, Goode, Scott
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970655/
https://ncbi.nlm.nih.gov/pubmed/20947521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1242
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