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Hippo Pathway Effector Yap is an Ovarian Cancer Oncogene

The Hippo Pathway regulates organ size and tumorigenesis in Drosophila and mammals and is altered in a variety of human cancers, yet it remains unclear if the Hippo Pathway is of prognostic significance to cancer patients. Here we show that Yap, the human homolog of the key transcriptional target of...

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Detalles Bibliográficos
Main Authors: Hall, Chad A., Wang, Runsheng, Miao, Jiangyong, Oliva, Esther, Shen, Xiaoyun, Wheeler, Thomas, Hilsenbeck, Susan G., Orsulic, Sandra, Goode, Scott
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970655/
https://ncbi.nlm.nih.gov/pubmed/20947521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1242
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