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Factor V has an anticoagulant cofactor activity that targets the early phase of coagulation

Tissue factor pathway inhibitor (TFPI), the main inhibitor of initiation of coagulation, exerts an important anticoagulant role through the factor Xa (FXa)-dependent inhibition of tissue factor/factor VIIa. Protein S is a TFPI cofactor, enhancing the efficiency of FXa inhibition. TFPI can also inhib...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Santamaria, Salvatore, Reglińska-Matveyev, Natalia, Gierula, Magdalena, Camire, Rodney M., Crawley, James T. B., Lane, David A., Ahnström, Josefin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454113/
https://ncbi.nlm.nih.gov/pubmed/28420729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.769570
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