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Factor V has an anticoagulant cofactor activity that targets the early phase of coagulation
Tissue factor pathway inhibitor (TFPI), the main inhibitor of initiation of coagulation, exerts an important anticoagulant role through the factor Xa (FXa)-dependent inhibition of tissue factor/factor VIIa. Protein S is a TFPI cofactor, enhancing the efficiency of FXa inhibition. TFPI can also inhib...
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| Published in: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5454113/ https://ncbi.nlm.nih.gov/pubmed/28420729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.769570 |
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