Kinetic-based trapping by intervening sequence variants of the active sites of protein-disulfide isomerase identifies platelet protein substrates

Thiol isomerases such as protein-disulfide isomerase (PDI) direct disulfide rearrangements required for proper folding of nascent proteins synthesized in the endoplasmic reticulum. Identifying PDI substrates is challenging because PDI catalyzes conformational changes that cannot be easily monitored...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Stopa, Jack D., Baker, Katherine M., Grover, Steven P., Flaumenhaft, Robert, Furie, Bruce
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Enzymology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454092/
https://ncbi.nlm.nih.gov/pubmed/28364042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.771832
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller