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Phagocytosis enhances lysosomal and bactericidal properties by activating the transcription factor TFEB
Macrophages internalize pathogens through phagocytosis, entrapping them into organelles called phagosomes. Phagosomes then fuse with lysosomes to mature into phagolysosomes, acquiring an acidic and hydrolytic lumen that kills the pathogens. During an ongoing infection, macrophages can internalize do...
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| Publicado no: | Curr Biol |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453720/ https://ncbi.nlm.nih.gov/pubmed/27397893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.05.070 |
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