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The complex relationship between TFEB transcription factor phosphorylation and subcellular localization

The MiT‐TFE family of basic helix‐loop‐helix leucine‐zipper transcription factors includes four members: TFEB, TFE3, TFEC, and MITF. Originally described as oncogenes, these factors play a major role as regulators of lysosome biogenesis, cellular energy homeostasis, and autophagy. An important mecha...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Puertollano, Rosa, Ferguson, Shawn M, Brugarolas, James, Ballabio, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983138/
https://ncbi.nlm.nih.gov/pubmed/29764979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798804
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