Cargando...

The Lysosomal Transcription Factor TFEB represses myelination downstream of the Rag-Ragulator complex

Myelin allows for fast and efficient axonal conduction, but much remains to be determined about the mechanisms that regulate myelin formation. To investigate the genetic basis of myelination, we carried out a genetic screen using zebrafish. Here we show that the lysosomal Gprotein RagA is essential...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Dev Cell
Main Authors: Meireles, Ana M, Shen, Kimberle, Zoupi, Lida, Iyer, Harini, Bouchard, Ellen L., Williams, Anna, Talbot, William S.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250074/
https://ncbi.nlm.nih.gov/pubmed/30399334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.10.003
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!