Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis

Fibrosis results from the dysregulation of tissue repair mechanisms affecting major organ systems, leading to chronic extracellular matrix buildup, and progressive, often fatal, organ failure. Current diagnosis relies on invasive biopsies. Noninvasive methods today cannot distinguish actively progre...

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Publicado en:JCI Insight
Main Authors: Chen, Howard H., Waghorn, Philip A., Wei, Lan, Tapias, Luis F., Schühle, Daniel T., Rotile, Nicholas J., Jones, Chloe M., Looby, Richard J., Zhao, Gaofeng, Elliott, Justin M., Probst, Clemens K., Mino-Kenudson, Mari, Lauwers, Gregory Y., Tager, Andrew M., Tanabe, Kenneth K., Lanuti, Michael, Fuchs, Bryan C., Caravan, Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453697/
https://ncbi.nlm.nih.gov/pubmed/28570270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91506
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