Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis

Fibrosis results from the dysregulation of tissue repair mechanisms affecting major organ systems, leading to chronic extracellular matrix buildup, and progressive, often fatal, organ failure. Current diagnosis relies on invasive biopsies. Noninvasive methods today cannot distinguish actively progre...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Chen, Howard H., Waghorn, Philip A., Wei, Lan, Tapias, Luis F., Schühle, Daniel T., Rotile, Nicholas J., Jones, Chloe M., Looby, Richard J., Zhao, Gaofeng, Elliott, Justin M., Probst, Clemens K., Mino-Kenudson, Mari, Lauwers, Gregory Y., Tager, Andrew M., Tanabe, Kenneth K., Lanuti, Michael, Fuchs, Bryan C., Caravan, Peter
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453697/
https://ncbi.nlm.nih.gov/pubmed/28570270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91506
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