Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis

Fibrosis results from the dysregulation of tissue repair mechanisms affecting major organ systems, leading to chronic extracellular matrix buildup, and progressive, often fatal, organ failure. Current diagnosis relies on invasive biopsies. Noninvasive methods today cannot distinguish actively progre...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Chen, Howard H., Waghorn, Philip A., Wei, Lan, Tapias, Luis F., Schühle, Daniel T., Rotile, Nicholas J., Jones, Chloe M., Looby, Richard J., Zhao, Gaofeng, Elliott, Justin M., Probst, Clemens K., Mino-Kenudson, Mari, Lauwers, Gregory Y., Tager, Andrew M., Tanabe, Kenneth K., Lanuti, Michael, Fuchs, Bryan C., Caravan, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453697/
https://ncbi.nlm.nih.gov/pubmed/28570270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91506
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