Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis

Fibrosis results from the dysregulation of tissue repair mechanisms affecting major organ systems, leading to chronic extracellular matrix buildup, and progressive, often fatal, organ failure. Current diagnosis relies on invasive biopsies. Noninvasive methods today cannot distinguish actively progre...

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Enregistré dans:
Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Chen, Howard H., Waghorn, Philip A., Wei, Lan, Tapias, Luis F., Schühle, Daniel T., Rotile, Nicholas J., Jones, Chloe M., Looby, Richard J., Zhao, Gaofeng, Elliott, Justin M., Probst, Clemens K., Mino-Kenudson, Mari, Lauwers, Gregory Y., Tager, Andrew M., Tanabe, Kenneth K., Lanuti, Michael, Fuchs, Bryan C., Caravan, Peter
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453697/
https://ncbi.nlm.nih.gov/pubmed/28570270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91506
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