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Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis

Fibrosis results from the dysregulation of tissue repair mechanisms affecting major organ systems, leading to chronic extracellular matrix buildup, and progressive, often fatal, organ failure. Current diagnosis relies on invasive biopsies. Noninvasive methods today cannot distinguish actively progre...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Chen, Howard H., Waghorn, Philip A., Wei, Lan, Tapias, Luis F., Schühle, Daniel T., Rotile, Nicholas J., Jones, Chloe M., Looby, Richard J., Zhao, Gaofeng, Elliott, Justin M., Probst, Clemens K., Mino-Kenudson, Mari, Lauwers, Gregory Y., Tager, Andrew M., Tanabe, Kenneth K., Lanuti, Michael, Fuchs, Bryan C., Caravan, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453697/
https://ncbi.nlm.nih.gov/pubmed/28570270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91506
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