(68)Ga-NODAGA-indole, an allysine-reactive positron emission tomography probe for molecular imaging of pulmonary fibrogenesis

Oxidized collagen, wherein lysine residues are converted to the aldehyde allysine, is a universal feature of fibrogenesis, i.e. actively progressive fibrosis. Here we report the small molecule, allysine-binding positron emission tomography (PET) probe, (68)Ga-NODAGA-indole, that can noninvasively de...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Wahsner, Jessica, Désogère, Pauline, Abston, Eric, Graham-O’Regan, Katherine A., Wang, Junfeng, Rotile, Nicholas J., Schirmer, Markus D., Ferreira, Diêgo Dos Santos, Sui, Jingyi, Fuchs, Bryan C., Lanuti, Michael, Caravan, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494104/
https://ncbi.nlm.nih.gov/pubmed/30908032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b12342
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