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Orthogonal luciferase-luciferin pairs for bioluminescence imaging

Bioluminescence imaging with luciferase-luciferin pairs is widely used in biomedical research. Several luciferases have been identified in nature, and many have been adapted for tracking cells in whole animals. Unfortunately, the optimal luciferases for imaging in vivo utilize the same substrate, an...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Jones, Krysten A., Porterfield, William B., Rathbun, Colin M., McCutcheon, David C., Paley, Miranda A., Prescher, Jennifer A.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452985/
https://ncbi.nlm.nih.gov/pubmed/28106389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11737
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