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Calculating site-specific evolutionary rates at the amino-acid or codon level yields similar rate estimates

Site-specific evolutionary rates can be estimated from codon sequences or from amino-acid sequences. For codon sequences, the most popular methods use some variation of the dN∕dS ratio. For amino-acid sequences, one widely-used method is called Rate4Site, and it assigns a relative conservation score...

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Bibliografiske detaljer
Udgivet i:PeerJ
Main Authors: Sydykova, Dariya K., Wilke, Claus O.
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452972/
https://ncbi.nlm.nih.gov/pubmed/28584717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3391
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